Lines of research Characterising the molecular determinants of apoptin's cytotoxicity and improving its targeted delivery to tumour cells Characterising the anti-tumour properties of ribonucleases targeted in cell nuclei and improving their internalisation efficiency Studying the anti-tumour properties of coordination compounds based on Fe(II), Cu (II) and Ru(II) and characterising the cytotoxic mechanisms of leading compounds. Studying the structure of TDP-43 through NMRs and the selective isotopic marking of the various domains using orthogonal inteins.