Grups de recerca > Microbiologia de la malaltia intestinal > Què oferim?
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Grup de Recerca en Microbiologia de la malaltia intestinal

Què oferim

Expertise and collaboration options

We are interested in collaborating with other research and health institutions. Therefore, we offer to perform the following analyses and assistance in the following topics:

We can assist in:

  • The quantification of specific targeted microbial groups.
  • The design and optimization of trials based on qPCR.
  • Determining the structure, composition and diversity of microbial communities of any nature, in both, cross-sectional or longitudinal studies.

We can assist in the isolation of strains from clinical or non-clinical samples up to biosafety level 2. An anaerobic chamber is available to culture anaerobic bacteria.

We can assist in the genetic characterization of isolates by PCR detection of virulence genes, sequencing genes to look for allelic variation, analysing clonality by pulsed field gel electrophoresis, and by genome and transcriptome sequencing.

We can test the hability of Escherichia coli strains to adhere and to invade intestinal epithelial cells and to survive and replicate within macrophages.

We can assist in analysis of bacterial and host genes differentially expressed.

 

We can test the effect of new antimicrobial compounds on different bacterial and yeast isolates.

We are able to generate knock-out mutants of Escherichia coli and Klebsiella pneumoniae as well as their counterparts ectopically complemented.

We can construct plasmids to express genes of interest in either eukaryotic cells or bacterial cells (Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii).

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