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Research Technical Services

Lyophilisation

It lyophilisation it is the process of sublimation of the water of a sample (step of liquid in gas) from the freezing of a sample and a posterior drying to the emptiness.

Job request

In order to carry out one analyses, put in touch with the responsible for the UEA.

It be necessary to inform of the toxicity and precautions of storage of the sample.

The equipment

Lyophilisation Telstar LyoQuest-55

Year:
2010



  Characteristics:

The LyoQuest-55 is a freeze drier compact and of easy installation. 

Have a capacity of 8 Kg of condenser (5 Kg/24 h), with a final temperature of -55 ºC.

The team is complemented with a bomb of emptiness of double stage placed in the exterior.

How does it work?

The foundation of the team of lyophilisation bases on maintaining temperature to casualty (-50ºC) a sample previously frozen while the emptiness is applied in a chamber. In this way the sublimation is obtained from the water contained in this sample. The process finishes when the internal temperature of the sample and of the chamber they become equal (between 24-48hr depending on the thickness of sample). How much more surface has the sample to freeze-dry and less amount of floating, faster it will be the process.

The objective of the lyophilisation is to dehydrate samples without altering its composition. The freeze-dried samples can be kept in fresh and dry places during a long period of time avoiding the degradation of these.

Applications / Practical cases

  • The lyophilisation can apply to any solid sample that contains water in its composition (foods, muds, cells, etc).
  • In mixtures of solid and water, it be necessary to let settle and to decant the floating one to shorten the process of lyophilisation.
  • It be necessary to avoid, as much as possible, the lyophilisation of samples that contain oils and other corrosive chemical products, since they could damage the team.

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