Pinsach-Abuin M; Del Olmo B; Pérez-Agustin A; Mates J; Allegue C; Iglesias A; Ma Q; Merkurjev D; Konovalov S; Zhang J; Sheikh F; Telenti A; Brugada J; Brugada R; Gymrek M; di Iulio J; Garcia-Bassets I and Pagans S. "Analysis of Brugada syndrome loci reveals that fine-mapping clustered GWAS hits enhances the annotation of disease-relevant variants." Cell Reports Medicine 2 (2021): 100250-. David Carreras, Rebecca Martinez-Moreno, Mel·lina Pinsach-Abuin, Manel M. Santafe, Pol Gomà, Ramon Brugada, Fabiana S. Scornik, Guillermo J. Pérez, Sara Pagans "Epigenetic Changes Governing Scn5a Expression in Denervated Skeletal Muscle." International Journal of Molecular Sciences 22 (2021): 2755-. Pérez-Agustín A; Pinsach-Abuin M; Pagans S. "Role of Non-Coding Variants in Brugada Syndrome." International Journal of Molecular Sciences 21 (2020): 8556-. Onwuli DO; Yañez-Bisbe L; Pinsach-Abuin M; Tarradas A; Brugada R; Greenman J; Pagans S*; Beltran-Alvarez P* "Do sodium channel proteolytic fragments regulate sodium channel expression?." Channels 11 (2017): 476-481. Boehm D; Jeng M; Camus G; Gramatica A; Schwarzer R; Johnson JR; Hull PA; Montano M; Sakane N; Pagans S; Godin R; Deeks SG; Krogan NJ; Greene WC; Ott M "SMYD2-Mediated Histone Methylation Contributes to HIV-1 Latency." Cell Host & Microbe 21 (2017): 569-579. Tarradas, A.; Pinsach-Abuin, M.L.; Mackintosh, C.; Llorà-Batlle, O.; Pérez-Serra, A.; Batlle, M.; Pérez-Villa, F.; Zimmer, T.; Garcia-Bassets, I.; Brugada, R.; Beltran-Alvarez, P.; Pagans, S. "Transcriptional regulation of the sodium channel gene (SCN5A) by GATA4 in human heart." Journal of Molecular and Cellular Cardiology 102 (2017): 74-82. Mademont-Soler, Irene ; Pinsach-Abuin, Mel·lina ; Riuró Cáceres, Helena ; Matés Ramírez, Jesús ; Pérez Serra, Alexandra ; Coll, Monica ; Porres, José M. ; Olmo, Bernat del ; Iglesias, Anna ; Selga Coma, Elisabet ; Picó, Ferra "Large Genomic Imbalances in Brugada Syndrome." PLoS One 11 (2016): e0163514-. Ali I; Ramage H; Boehm D; Dirk L; Sakane N; Hanada K; Pagans S; Kaehlcke K; Aull K; Weinberger L; Trievel R; Schnoelzer M; Kamada M; Houtz R; Ott M. "The HIV-1 Tat protein is monomethylated at lysine-71 by the lysine methyltransferase KMT7." the journal of biological chemistry 291 (2016): 16240-16248. Selga Coma, Elisabet; Campuzano Larrea, Oscar; Pinsach-Abuin, Mel·lina; Pérez Serra, Alexandra; Mademont-Soler, Irene; Riuró Cáceres, Helena; Picó, Ferran; Coll, Monica; Iglesias, Anna; Pagans i Lista, Sara; Sarquella-Brugada "Comprehensive Genetic Characterization of a Spanish Brugada Syndrome Cohort." PLoS One 10 (2015): e0132888-. Peeters, U; Scornik, F; Riuró, H; Pérez, G; Komurcu-Bayrak, E; Van Malderen, S; Pappaert, G; Tarradas, A; Pagans, S; Daneels, D; Breckpot, K; Brugada, P; Bonduelle, M; Brugada, R; Van Dooren, S "Contribution of cardiac sodium channel β-subunit variants to Brugada syndrome." Circulation Journal 79 (2015): 2118-2129. Beltran-Alvarez P; Feixas F; Osuna S; Díaz-Hernandez R; Brugada R; Pagans S. "Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel." Amino Acids 47 (2014): 429-434. Beltran-Alvarez P; Tarradas A; Chiva C; Pérez-Serra A; Batlle M; Perez-Villa F; Shulte U; Sabidó E; Brugada R; Pagans S. "Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart." Journal of Molecular and Cellular Cardiology 76 (2014): 126-129. Beltran-Alvarez P; Espejo A; Schmauder R; Beltran C; Mrowka R; Linke T; Batlle M; Pérez-Villa F; Pérez GJ; Scornik FS; Benndorf K; Pagans S; Zimmer T; Brugada R. "Protein arginine methyl transferases-3 and -5 increase cell surface expression of cardiac sodium channel.." Febs Letters 587 (2013): 3159-3165. Riuró, H; Beltran-Alvarez, P; Tarradas, A; Selga, E; Campuzano, O; Vergés, M; Pagans, S; Iglesias, A; Brugada, J; Brugada, P; Vázquez, FM; Pérez, GJ; Scornik, FS; Brugada R. "A missense mutation in the sodium channel β2 subunit reveals SCN2B as a new candidate gene for Brugada Syndrome." Human Mutation 34 (2013): 961-966. Beltran-Alvarez P; Pagans S; Brugada R. "The Cardiac Sodium Channel Is Post-Translationally Modified by Arginine Methylation." Journal of Proteome Research 10 (2011): 3712-3719. Sakane N; Kwon HS; Pagans S; Kaehlcke K; Mizusawa Y; Kamada M; Shi Y; Schnolzer M; Ott M. "Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1)." PLoS Pathogens 7 (2011): e1002184-. Pagans S; Sakane N; Schnolzer M; Ott M. "Characterization of HIV Tat modifications using novel methyl-lysine-specific antibodies." Methods-A Companion to Methods in Enzymology 53 (2011): 91-96. Pagans S; Kauder S; Kaehlcke K; Sakane N; Schroeder S; Dormeyer W; Trievel RC; Verdin E; Ott M. "The Cellular Lysine Methyltransferase Set7/9-KMT7 Binds HIV-1 TAR RNA, Monomethylates the Viral Transactivator Tat, and Enhances HIV Transcription." Cell Host & Microbe 7 (2010): 234-244. Pagans S; Pedal A; North BJ; Kaehlcke K; Marshall BL; Dorr A; Hetzer-Egger C; Henklein P; Frye R; McBurney MW; Hruby H; Jung M; Verdin E; Ott M. "SIRT1 regulates HIV transcription via Tat deacetylation." Plos Biology 3 (2005): 210-220. Pagans S; Piñeyro D; Kosoy A; Bernués J; Azorín F. "Repression by TTK69 of GAGA-mediated activation occurs in the absence of TTK69 binding to DNA and solely requires the contribution of the POZ/BTB domain of TTK69." the journal of biological chemistry 279 (2004): 9725-9732. Kosoy A; Pagans S; Espinás M L; Azorín F; Bernués J. "GAGA factor down-regulates its own promoter." the journal of biological chemistry 277 (2002): 42280-42288. Pagans S; Ortiz-Lombardía M; Espinás M L; Bernués J; Azorín F. "The Drosophila transcription factor tramtrack (TTK) interacts with Trithorax-like (GAGA) and represses GAGA-mediated activation." Nucleic Acids Research 30 (2002): 4406-4413. García-Bassets I; Ortiz-Lombardía M; Pagans S; Romero A; Canals F; Avilés FX; Azorín F. "The identification of nuclear proteins that bind the homopyrimidine strand of d(GA•TC)n DNA sequences, but not the homopurine strand." Nucleic Acids Research 27 (1999): 3267-3275.
Pagans, S.; Verges, M. "A mechanism for NaV1.5 downregulation and sodium current decrease in heart failure." Acta Physiologica 221 (2017): 11-13.