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Grup de Recerca en Noves Dianes Terapèutiques

Publicacions

Impacte científic

Articles

Espinosa Mirabet S, Costa Gálvez L. (2020). Identidad gráfica para un equipo de biomedicina universitario: consiguiendo notoriedad / Graphic identity for a biomedical university team: gaining visibility. Revista Internacional de Relaciones Públicas, 10(19). doi: http://dx.doi.org/10.5783/RIRP-19-2020-11-201-222

Giró-Perafita A, Rabionet M, Planas M, Feliu L, Ciurana J, Ruiz-Martínez S, Puig T. (2019). EGCG-Derivative G28 Shows High Efficacy Inhibiting the Mammosphere-Forming Capacity of Sensitive and Resistant TNBC Models. Molecules, 24(6). pii: E1027. doi: 10.3390/molecules24061027

Palomeras S, Diaz-Lagares Á, Viñas G, Setien F, Ferreira HJ, Oliveras G, Crujeiras AB, Hernández A, Lum DH, Welm AL, Esteller M, Puig T. (2019) Epigenetic silencing of TGFBI confers resistance to trastuzumab in human breast cancer.Breast Cancer Res, 21(1), 79. doi: 10.1186/s13058-019-1160-x

Polonio-Alcalá E, Rabionet M, Gallardo X, Angelats D, Ciurana J, Ruiz-Martínez S, Puig T. (2019). PLA Electrospun Scaffolds for Three-Dimensional Triple-Negative Breast Cancer Cell Culture. Polymers (Basel), 11(5). pii: E916. doi: 10.3390/polym11050916

Polonio-Alcalá E, Rabionet M, Ruiz-Martínez S, Ciurana J, Puig T. (2019). Three-Dimensional Manufactured Supports for Breast Cancer Stem Cell Population Characterization. Curr Drug Targets, 20(8),839-851. doi: 10.2174/1389450120666181122113300

Puig T, Ciurana J. (2019) Nanotechnology in Biomedical Applications. Curr Drug Targets. 2019;20(8),799. doi: 10.2174/138945012008190409125917

Crous-Masó, J., Palomeras, S., Relat, J., Camó, C., Martínez-Garza, Ú., Planas, M., Feliu, L., Puig, T. (2018). (−)-Epigallocatechin 3-gallate synthetic analogues inhibit fatty acid synthase and show anticancer activity in triple negative breast cancer. Molecules, 23. doi:10.3390/molecules23051160

Guerra, A. J., Cano, P., Rabionet, M., Puig, T., Ciurana, J. (2018). Effects of different sterilization processes on the properties of a novel 3D-printed polycaprolactone stent. Polym. Adv. Technol., 29, 2327-2335. doi:10.1002/pat.4344

Kühne, B. A., Puig, T., Ruiz-Martínez, S., Crous-Masó, J., Planas, M., Feliu, L., Cano, A., Garcia, M. L., Fritsche, E., Llobet, J. M., Gómez-Catalán, J., Barenys, M. (2018). Comparison of migration disturbance potency of epigallocatechin gallate (EGCG) synthetic analogs and EGCG PEGylated PLGA nanoparticles in rat neurospheres. Food Chem. Toxicol, 123, 195-204. doi:10.1016/j.fct.2018.10.055

Palomeras, S., Ruiz-Martínez, S., Puig, T. (2018). Targeting Breast Cancer Stem Cells to Overcome Treatment Resistance. Molecules, 23, 2193. doi:10.3390/molecules23092193

Polonio-Alcalá, E., Rabionet, M., Guerra, A., Yeste, M., Ciurana, J., Puig, T., Polonio-Alcalá, E., Rabionet, M., Guerra, A. J., Yeste, M., Ciurana, J., Puig, T. (2018). Screening of Additive Manufactured Scaffolds Designs for Triple Negative Breast Cancer 3D Cell Culture and Stem-Like Expansion. Int. J. Mol. Sci., 19, 3148. doi:10.3390/ijms19103148

Polonio-Alcalá, E., Rabionet, M., Ruiz-Martínez, S., Ciurana, J., Puig, T. (2018). Three-Dimensional Manufactured Supports for Breast Cancer Stem Cell Population Characterization. Curr. Drug Targets, 21. doi:10.2174/1389450120666181122113300

Rabionet, M., Guerra, A. J., Puig, T., Ciurana, J. (2018). 3D-printed Tubular Scaffolds for Vascular Tissue Engineering. Procedia CIRP, 68, 352-357. doi:10.1016/J.PROCIR.2017.12.094

Rabionet, M., Polonio, E., Guerra, A., Martin, J., Puig, T., Ciurana, J. (2018). Design of a Scaffold Parameter Selection System with Additive Manufacturing for a Biomedical Cell Culture. Materials (Basel), 11, 1427. doi:10.3390/ma11081427

Bosch-Mola, M., Homs, J., Álvarez-Pérez, B., Puig, T., Reina, F., Verdú, E., Boadas-Vaello, P. (2017). (-)-Epigallocatechin-3-Gallate Antihyperalgesic Effect Associates With Reduced CX3CL1 Chemokine Expression in Spinal Cord. Phytother. Res., 31, 340–344. doi:10.1002/ptr.5753

Giró-Perafita, A., Sarrats, A., Pérez-Bueno, F., Oliveras, G., Buxó, M., Brunet, J., Viñas, G., Puig Miquel, T. (2017). Fatty acid synthase expression and its association with clinico-histopathological features in triple-negative breast cancer. Oncotarget, 8, 74391-74405. doi:10.18632/oncotarget.20152

Menyhart, O., Budczies, J., Munkácsy, G., Esteva, F. J., Szabó, A., Miquel, T. P., Győrffy, B. (2017). DUSP4 is associated with increased resistance against anti-HER2 therapy in breast cancer. Oncotarget, 8, 77207-77218. doi:10.18632/oncotarget.20430

Rabionet, M., Yeste, M., Puig, T., Ciurana, J. (2017). Electrospinning PCL scaffolds manufacture for three-dimensional breast cancer cell culture. Polymers (Basel), 9, 1-15. doi:10.3390/polym9080328

Álvarez-Pérez, B., Homs, J., Bosch-Mola, M., Puig, T., Reina, F., Verdú, E., Boadas-Vaello, P. (2016). Epigallocatechin-3-gallate treatment reduces thermal hyperalgesia after spinal cord injury by down-regulating RhoA expression in mice. Eur. J. Pain, 20, 341-352. doi:10.1002/ejp.722

Carreras-Badosa, G., Prats-Puig, A., Puig, T., Vázquez-Ruíz, M., Bruel, M., Mendoza, E., de Zegher, F., Ibáñez, L., López-Bermejo, A., Bassols, J. (2016). Circulating Fatty Acid Synthase in pregnant women: Relationship to blood pressure, maternal metabolism and newborn parameters. Sci. Rep., 6, 24167. doi:10.1038/srep24167

Colomer, R., Sarrats, A., Lupu, R., Puig, T. Natural Polyphenols and their Synthetic Analogs as Emerging Anticancer Agents. (2016). Curr. Drug Targets, 18, 147-159. doi:10.2174/1389450117666160112113930

Giró-Perafita, A., Palomeras, S., Lum, D. H., Blancafort, A., Viñas, G., Oliveras, G., Pérez-Bueno, F., Sarrats, A., Welm, A. L., Puig, T. (2016). Preclinical Evaluation of Fatty Acid Synthase and EGFR Inhibition in Triple Negative Breast Cancer. Clin. Cancer Res., 22, 4687-4697. doi:10.1158/1078-0432

Palomeras, S., Rabionet, M., Ferrer, I., Sarrats, A., Garcia-Romeu, M. L., Puig, T., Ciurana, J. (2016). Breast Cancer Stem Cell Culture and Enrichment Using Poly(ϵ-Caprolactone) Scaffolds. Molecules, 21, 1-14. doi:10.3390/molecules21040537

Prats-Puig, A., Soriano-Rodríguez, P., Oliveras, G., Carreras-Badosa, G., Espuña, S., Díaz-Roldán, F., de Zegher, F., Ibáñez, L., Bassols, J., Puig, T., López-Bermejo, A. (2016). Soluble CRTC3: A Newly Identified Protein Released by Adipose Tissue That Is Associated with Childhood Obesity. Clin. Chem., 62, 476-84. doi:10.1373/clinchem.2015.249136

Blancafort, A., Giró-Perafita, A., Oliveras, G., Palomeras, S., Turrado, C., Campuzano, Ò., Carrión-Salip, D., Massaguer, A., Brugada, R., Palafox, M., Gómez-Miragaya, J., González-Suárez, E., Puig, T. (2015). Dual fatty acid synthase and HER2 signaling blockade shows marked antitumor activity against breast cancer models resistant to anti-HER2 drugs. PLoS One, 10, e0131241. doi:10.1371/journal.pone.0131241

Porta, R., Blancafort, A., Casòliva, G., Casas, M., Dorca, J., Buxo, M., Viñas, G., Oliveras, G., Puig, T. (2014). Fatty acid synthase expression is strongly related to menopause in early-stage breast cancer patients. Menopause, 21, 188-91. doi:10.1097/GME.0b013e31829d17dc

Relat, J., Blancafort, A., Oliveras, G., Cufí, S., Haro, D., Marrero, P. F., Puig, T. (2012). Different fatty acid metabolism effects of (-)-epigallocatechin-3-gallate and C75 in adenocarcinoma lung cancer. BMC Cancer, 12, 280. doi:10.1186/1471-2407-12-280

Puig, T., Aguilar, H., Cufí, S., Oliveras, G., Turrado, C., Ortega-Gutiérrez, S., Benhamú, B., López-Rodríguez, M. L., Urruticoechea, A., Colomer, R. (2011). A novel inhibitor of fatty acid synthase shows activity against HER2+ breast cancer xenografts and is active in anti-HER2 drug-resistant cell lines. Breast Cancer Res., 13, R131. doi:10.1186/bcr3077

Oliveras, G., Blancafort, A., Urruticoechea, A., Campuzano, O., Gómez-Cabello, D., Brugada, R., López-Rodríguez, M. L., Colomer, R., Puig, T. (2010). Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer. Ann. N. Y. Acad. Sci., 1210, 86-92. doi:10.1111/j.1749-6632.2010.05777

Puig, T., Porta, R., Colomer, R. (2009). Fatty acid synthase: a new anti-tumor target. Med. Clin. (Barc)., 132, 359-63. doi:10.1016/j.medcli.2008.07.022

Puig, T., Turrado, C., Benhamu, B., Aguilar, H., Relat, J., Ortega-Gutierrez, S., Casals, G., Marrero, P. F., Urruticoechea, A., Haro, D., Lopez-Rodriguez, M. L., Colomer, R., Benhamú, B., Aguilar, H., Relat, J., Ortega-Gutiérrez, S., Casals, G., Marrero, P. F., Urruticoechea, A., Haro, D., López-Rodríguez, M. L., Colomer, R. (2009). Novel Inhibitors of Fatty Acid Synthase with Anticancer Activity. Clin. Cancer Res., 15, 7608-7615. doi:10.1158/1078-0432.CCR-09-0856

Puig, T., Relat, J., Marrero, P. F., Haro, D., Brunet, J., Colomer, R. (2008). Green tea catechin inhibits fatty acid synthase without stimulating carnitine palmitoyltransferase-1 or inducing weight loss in experimental animals. Anticancer Res., 28, 3671-6.

Proceedings

Dissertations

Castro Fernàndez, T.; Quintana, A. & Ribera, L. (2019). Creació d’un esdeveniment solidari: Emerging Market (treball final de grau). Universitat de Girona, Girona. Dir. Sílvia Espinosa Mirabet.

Corominas Salvaña, J. (2018). Desenvolupament d’un web pel grup de recerca Targetslab (treball final de grau). Universitat de Girona, Girona. Dir. Sílvia Espinosa Mirabet.

Garcia Molinero, A. & Ramírez Ricarte, A. Projecte audiovisual per Targetslab (treball final de grau). Universitat de Girona, Girona. Dir. Sílvia Espinosa Mirabet.

Ribera Quintes, C. (2018). Organització d’una Jornada solidària per impulsar la investigació mèdica del grup de recerca Targetslab (treball final de grau). Universitat de Girona, Girona. Dir. Sílvia Espinosa Mirabet.

Salamo Formiga, P. (2019). Oncoen3D. Desenvolupament d’una identitat visual corporativa d’un grup de recerca en enginyeria biomèdica a la Universitat de Girona (treball final de grau). Universitat de Girona, Girona. Dir. Sílvia Espinosa Mirabet.

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