Jorge Leal; Lucia Santos; Diego M. Fernández-Aroca; J. Vicente Cuevas; M. Angeles Martínez; Anna Massaguer; Felix A. Jalón; M. José Ruiz-Hidalgog; Ricardo Sánchez-Prieto; Ana M. Rodríguez; Gregorio Castañeda; Gema Durá; M. Ca "Effect of the aniline fragment in Pt(II) and Pt(IV) complexes as anti-proliferative agents. Standard reduction potential as a more reliable parameter for Pt(IV) compounds than peak reduction potential.." Journal of Inorganic Biochemistry (2021): -. Pedro Enrique Guerrero , Laura Miró, Bin S Wong,, Anna Massaguer, Neus Martínez-Bosch, Rafael de Llorens, Pilar Navarro, Konstantinos Konstantopoulos, Esther Llop, Rosa Peracaula "Knockdown of α2,3-Sialyltransferases Impairs Pancreatic Cancer Cell Migration, Invasion and E-selectin-Dependent Adhesion." International Journal of Molecular Sciences (2020): -. Barrabés, S.; Ng-Choi, I.; Martínez, M.A.; Manzano, B.R.; Jalón, F.A.; Espino, G.; Feliu, L.; Planas, M.; de Llorens, R.; Massaguer, A. "A nucleous-directed bombesin derivative for targeted delivery of metallodrugs to cancer cells." Journal of Inorganic Biochemistry 212 (2020): 111214-. Rovira A, Gandioso A, Goñalons M, Galindo A, Massaguer A, Bosch M, Marchán V. "Solid-Phase Approaches for Labeling Targeting Peptides with Far-Red Emitting Coumarin Fluorophores.." Journal of Organic Chemistry 84(4):1808-1817 (2019): 1808-1817. Zamora A, Gandioso A, Massaguer A, Buenestado S, Calvis C, Hernández JL, Mitjans F, Rodríguez V, Ruiz J, Marchán V. "Toward Angiogenesis Inhibitors Based on the Conjugation of Organometallic Platinum(II) Complexes to RGD Peptides.." ChemMedChem 13 (2018): 1755-1765. Llop E, E Guerrero P, Duran A, Barrabés S, Massaguer A, José Ferri M, Albiol-Quer M, de Llorens R, Peracaula R. "Glycoprotein biomarkers for the detection of pancreatic ductal adenocarcinoma." World Journal of Gastroenterology 24 (2018): 2537-2554. Martínez MÁ, Carranza MP, Massaguer A, Santos L, Organero JA, Aliende C, de Llorens R, Ng-Choi I, Feliu L, Planas M, Rodríguez AM, Manzano BR, Espino G, Jalón FA. "Synthesis and Biological Evaluation of Ru(II) and Pt(II) Complexes Bearing Carboxyl Groups as Potential Anticancer Targeted Drugs." Inorganic Chemistry 56 (2017): 13679-13696. Gandioso, A., Massaguer, A., Villegas, N., Salvans, C., Sánchez, D., Brun-Heath, I., Marchán, V., Orozco, M., Terrazas, M. "Efficient siRNA-peptide conjugation for specific targeted delivery into tumor cells." Chemical Communications 53 (2017): 2870-2873. Soler, Marta; González-Bártulos, Marta; Figueras, Eduard; Massaguer, Anna; Feliu, Lidia; Planas, Marta; Ribas, Xavi; Costas, Miquel "Delivering aminopyridine ligands into cancer cells through conjugation to the cell-penetrating peptide BP16." Organic and Biomolecular Chemistry 14 (2016): 4061-4070. Shaili E, Fernández-Giménez M, Rodríguez-Astor S, Gandioso A, Sandín L, García-Vélez C, Massaguer A, Clarkson GJ, Woods JA, Sadler PJ, Marchán V. "A Photoactivatable Platinum(IV) Anticancer Complex Conjugated to the RNA Ligand Guanidinoneomycin.." Chemistry-A European Journal (2015): -. Panosa C, Fonge H, Ferrer-Batallé M, Menéndez JA, Massaguer A, De Llorens R, Reilly RM. "A comparison of non-biologically active truncated EGF (EGFt) and full-length hEGF for delivery of Auger electron-emitting 111In to EGFR-positive breast cancer cells and tumor xenografts in athymic mice.." Nuclear Medicine and Biology 42 (2015): 931-938. Soler, M; Figueras, E; Serrano-Plana, J; González-Bártulos, M; Massaguer, A; Company, A; Martínez, MA; Malina, J; Brabek, V; Feliu, L; Planas, M; Ribas, X; and Costas, M "Design, preparation and characterization of Zn and Cu metallopeptides based on tetradentate aminopyridine ligands showing enhanced DNA cleavage activity." Inorganic Chemistry 54 (2015): 10542-10558. González-Bártulos, Marta; Aceves-Luquero, Clara; Qualai, Jamal; Cussó, Olaf; Martínez, Mª Angeles; Fernández de Mattos, Silvi; Menéndez, Javier A.; Villalonga, Priam; Costas, Miquel; Ribas, Xavi; Massaguer, Anna "Pro-Oxidant Activity of Amine-Pyridine-Based Iron Complexes Efficiently Kills Cancer and Cancer Stem-Like Cells." PLoS One 10 (2015): e0137800-. Blancafort, A; Giro-Perafita, A; Oliveras, G; Palomeras, S; Turrado, C; Campuzano, O; Carrion-Salip, D; Massaguer, A; Brugada, R; Palafox, M; Gomez-Miragaya, J; Gonzalez-Suarez, E; Puig, T "Dual Fatty Acid Synthase and HER2 Signaling Blockade Shows Marked Antitumor Activity against Breast Cancer Models Resistant to Anti-HER2 Drugs." PLoS One 10 (2015): e0131241-. Gandioso A, Shaili E, Massaguer A, Artigas G, González-Cantó A, Woods JA, Sadler PJ, Marchán V "An integrin-targeted photoactivatable Pt(iv) complex as a selective anticancer pro-drug: synthesis and photoactivation studies." Chemical Communications 51 (2015): 9169-9172. Cuyàs, E; Martin-Castillo, B; Corominas-Faja, B; Massaguer, A; Bosch-Barrera, J; Menendez, J.A. "Anti-protozoal and anti-bacterial Antibiotics that inhibit protein synthesis kill Cancer subtypes enriched for stem cell-like properties." Cell Cycle 14 (2015): 3527-3532. Marta Soler, Marta González, Eduard Figueras, Xavi Ribas, Miquel Costas, Anna Massaguer, Lidia Feliu, Marta Planas "Enzyme-triggered delivery of chlorambucil from conjugates based on the cell-penetrating peptide BP16." Organic and Biomolecular Chemistry 13 (2015): 1470-1480. Anna Massaguer; Alejandro González-Cantó; Esther Escribano; Silvia Barrabés; Gerard Artigas; Virtudes Moreno; Vicente Marchán "Integrin-targeted delivery into cancer cells of a Pt(IV) pro-drug through conjugation to RGD-containing peptides.." Dalton Transactions 44 (2014): 202-212. Marta Soler, Marta González, David Soriano-Castell, Xavi Ribas, Miquel Costas, Francesc Tebar, Anna Massaguer, Lidia Feliu, Marta Planas "Identification of BP16 as a non-toxic cell-penetrating peptide with highly efficient drug delivery properties." Organic and Biomolecular Chemistry 12 (2014): 1652-1663. Sekhar SC; Kasai T; Satoh A; Shigehiro T; Mizutani A; Murakami H; El-Aarag BY; Salomon DS; Massaguer A; de Llorens R; Seno M "Identification of caveolin-1 as a potential causative factor in the generation of trastuzumab resistance in breast cancer cells." Journal Of Cancer 4 (2013): 391-401. Panosa C; Tebar F; Ferrer-Batallé M; Fonge H; Seno M; Reilly RM; Massaguer A; De Llorens R. "Development of an epidermal growth factor derivative with EGFR blocking activity." PLoS One 8 (2013): e69325-. Sekhar SC, Kasai T, Satoh A, Shigehiro T, Mizutani A, Murakami H, El-Aarag B, Salomon DS, Massaguer A, de Llorens R, Seno M. "“Identification of Caveolin-1 as a Potential Causative Factor in the Generation of Trastuzumab Resistance in Breast Cancer Cells. ." Journal Of Cancer 4 (2013): 391-401. Grau-Campistany A, Massaguer A, Carrion-Salip D, Barragán F, Artigas G, López-Senín P, Moreno V, Marchán V "Conjugation of a Ru(II) arene complex to neomycin or to guanidinoneomycin leads to compounds with differential cytotoxicities and accumulation between cancer and normal cells.." Molecular Pharmaceutics 10 (2013): 1964-1976. Aliende, C.; Pérez-Manrique, M.; Jalón, F.A.; Manzano, B.R.; Rodríguez, A.M.; Cuevas, J.V.; Espino, G.; Martinez, M.A.; Massaguer, A.; González-Bártulos, M.; LLorens, R.; Moreno, V. "Preparation of new half sandwich ruthenium arene complexes with aminophosphines as potential chemotherapeutics." Journal of Inorganic Biochemistry 117 (2012): 171-188. Barragán, Flavia ; Carrion Salip, Dolors ; Gómez-Pinto, Irene ; González-Cantó, Alejandro ; Sadler, Peter J. ; Llorens Duran, Rafael de ; Moreno, Virtudes ; González Ibañez, Carlos ; Massaguer i Vall-llovera, Anna ; Marchán, "Somatostatin subtype 2 receptor-targeted metal-based anticancer complexes." Bioconjugate Chemistry 23 (2012): 1838-1855. Carrion-Salip D; Panosa C; Menendez JA; Puig T; Oliveras G; Pandiella A; Llorens R; Massaguer A "Androgen-independent prostate cancer cells circumvent EGFR inhibition by overexpression of alternative HER receptors and ligands." International Journal of Oncology 41 (2012): 1128-1138. Oliveras-Ferraros, Cristina; Massaguer Vall-llovera, Anna; Carrion Salip, Dolors; Vazquez-Martin, Alejandro; Cufí, Silvia; Queralt, Bernardo; Martin-Castillo, Begoña; Brunet, Joan; Llorens, Rafael de; Menéndez, Javier A. "Evolution of the predictive markers amphiregulin and epiregulin mRNAs during long-term cetuximab treatment of KRAS wild-type tumor cells." Investigational New Drugs 30 (2012): 846-852. Cristina Oliveras-Ferraros; Anna Massaguer Vall-Llovera; Alejandro Vazquez-Martin; Dolors Carrion Salip; Bernardo Queralt; Silvia Cufí; Begoña Martin-Castillo; Joaquim Bosch-Barrera; Joan Brunet; Rafael De Llorens; Javier A. "Transcriptional upregulation of HER2 expression in the absence of HER2 gene amplification results in cetuximab resistance that is reversed by trastuzumab treatment.." Oncology Reports 27 (2012): 1887-1892. Ramirez S, Perez-Del-Pulgar S, Carrion JA, Costa J, Gonzalez P, Massaguer A, Fondevila C, Garcia-Valdecasas JC, Navasa M, Forns X. "Hepatitis C virus compartmentalization and infection recurrence after liver transplantation.." American Journal of Transplantation 9 (2009): 1591-1601. Massaguer, A.; Ramirez, S.; Carrion, J.A.; Gonzalez, P.; Sanchez-Tapias, J.M.; Forns. X. "Evolution of the NS3 and NS5B regions of the hepatitis C virus during disease recurrence after liver transplantation." American Journal of Transplantation 7 (2007): 2172-2179. Feliu, A.; Carrion, J.A.; Massaguer, A.; Martinez-Bauer, E.; García-Retortillo, M.; Gonzalez, P.; Costa, J.; Sánchez-Tapias, J.M.; Forns, X. "Sensitivity to antiviral therapy may change after liver transplantation in patients with chronic hepatitis C virus infection." Journal of Viral Hepatitis 13 (2006): 544-551. Massaguer, A.; Forns, X.; Costa, J.; Feliu, A.; García-Retortillo, M.; Navasa, M.; Rimola, A.; García-Valdecasas, J.C.; Sánchez-Tapias, J.M. "Performance of hepatitis c virus (HCV) core antigen immunoassay to monitor viral load after liver transplantation." Transplantation 79 (2005): 1441-1444. Solanes, N.; Rigol, M.; Khabiri, E.; Castella, M.; Ramirez, J.; Roque, M.; Agusti, E.; Roig, E.; Perez-Villa, F.; Segales, J.; Pomar, J.L.; Engel, P.; Massaguer, A.; Martorell, J.; Rodriguez, J.A.; Sanz, G.; Heras, M. "Effects of cryopreservation on the immunogenicity of porcine arterial allografts in early stages of transplant vasculopathy." Cryobiology 51 (2005): 130-141. March, S.; Garcia-Pagan, J.C.; Massaguer, A.; Pizcueta, P.; Panes, J.; Engel, P.; Bosch, J. "P-selectin mediates leukocyte rolling in concanavalin-A-induced hepatitis." Liver International 25 (2005): 1053-1060. Barrabes, J.A.; Garcia-Dorado, D.; Mirabet, M.; Inserte, J.; Agullo, L.; Soriano, B.; Massaguer, A.; Padilla, F.; Lidon, R.M.; Soler-Soler, J. "Antagonism of selectin function attenuates microvascular platelet deposition and platelet-mediated myocardial injury after transient ischemia." Journal of the American College of Cardiology 45 (2005): 293-299. Soriano-Izquierdo A, Gironella M, Massaguer A, Salas A, Gil F, Pique JM, Panes J. "Effect of cyclosporin A on cell adhesion molecules and leukocyte-endothelial cell interactions in experimental colitis.." Inflammatory Bowel Diseases 10 (2004): 789-800. Garcia-Retortillo M, Forns X, Llovet JM, Navasa M, Feliu A, Massaguer A, Bruguera M, Fuster J, Garcia-Valdecasas JC, Rimola A "Hepatitis C recurrence is more severe after living donor compared to cadaveric liver transplantation. ." Hepatology 40 (2004): 699-707. Soriano-Izquierdo A, Gironella M, Massaguer A, May FE, Salas A, Sans M, Poulsom R, Thim L, Pique JM, Panes J "Trefoil peptide TFF2 treatment reduces VCAM-1 expression and leukocyte recruitment in experimental intestinal inflammation." Journal of Leukocyte Biology 75 (2004): 214-223. Massaguer A, Engel P, Tovar V, March S, Rigol M, Solanes N, Bosch J, Pizcueta P "Characterization of platelet and soluble-porcine P-selectin (CD62P)." Veterinary Immunology and Immunopathology 96 (2003): 169-181. Massaguer A., Perez-del-Pulgar S., Engel P., Serratosa J., Bosch J., Pizcueta P "Concanavalin-A-induced liver injury is severely impaired in mice deficient in P-selectin." Journal of Leukocyte Biology 72 (2002): 262-270. Mirabet M, Garcia-Dorado D, Inserte J, Barrabis JA, Lidsn RM, Soriano B., Azevedo M., Padilla F., Agullo L., Ruiz-Meana M., Massaguer A., Pizcueta P., Soler-Soler J. "Platelets activated by transient coronary occlusion exacerbate ischemia-reperfusion injury in rat hearts." American Journal of Physiology. Heart and Circulatory Physiology 283 (2002): H1134-H1141. Graupera M., García-Pagán JC., Titos E., Claria J., Massaguer A., Bosch J., Rodés J. "5-lipoxygenase inhibition decreases the intrahepatic vascular resistance of cirrhotic rat livers. A possible role of cysteinyl-leukotrienes." Gastroenterology 122 (2002): 387-393. Massaguer,A.; Haro,I.; Alsina,M.A.; Reig,F "Synthesis of RGD containing peptides. Comparative study of their incorporation to the surface of 5-fluoruridine loaded liposomes." Journal of Liposome Research 11 (2001): 103-113. Massaguer A., Perez del Pulgar S., Bosch J., Engel P., Pizcueta P "Production and characterization of P-selectin monoclonal antibodies against conserved epitopes." Tissue Antigens 56 (2000): 117-128.
Gandioso A, Cano M, Massaguer A, Marchán V. "A Green Light-Triggerable RGD Peptide for Photocontrolled Targeted Drug Delivery: Synthesis and Photolysis Studies." Journal of Organic Chemistry 81 (2016): 11556-11564.