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Estudia a la UdG

Dades generals

Curs acadèmic:
2020
Descripció:
Estructura i composició de les partícules virals. Origen in filogènia. Cicle viral i regulació lisis/lisogènia. Ecologia i patogènia viral. Mètodes de quantificació de partícules virals.
Crèdits ECTS:
3

Grups

Grup BB

Durada:
Semestral, 2n semestre
Professorat:
CARLES BORREGO MORE  / JOAN CALIZ GELADOR
Idioma de les classes:
Anglès (100%)

Grup BL

Durada:
Semestral, 2n semestre
Professorat:
CARLES BORREGO MORE  / JOAN CALIZ GELADOR
Idioma de les classes:
Anglès (100%)

Grup BT

Durada:
Semestral, 2n semestre
Professorat:
CARLES BORREGO MORE  / JOAN CALIZ GELADOR
Idioma de les classes:
Anglès (100%)

Competències

  • Capacitat per analitzar críticament a partir de la recollida d'informació i la interpretació de dades , situacions complexes i dissenyar estratègies creatives i innovadores per resoldre-les.
  • Saber comunicar-se oralment i per escrit en l'àmbit científic i professional , utilitzant les llengües pròpies i l'anglès.
  • Treballar en equip contribuint a l'elaboració de projectes específics i multidisciplinaris.
  • Planificar i avaluar la pròpia activitat i el propi aprenentatge i elaborar estratègies per millorar-los aplicant criteris de qualitat.
  • Capacitat per actuar, generar propostes i prendre decisions en la investigació i en l'activitat professional amb criteris ètics i de sostenibilitat.
  • Utilitzar i aplicar de forma segura la instrumentació i les metodologies experimentals pròpies de la disciplina.
  • Identificar i entendre , a nivell estructural i funcional , les bases moleculars de les estructures i els processos biològics , les seves aplicacions i els mecanismes de regulació.
  • Descriure , a nivell estructural i funcional , les bases cel·lulars i fisiològiques dels éssers vius.

Continguts

1. LECTURES (Large-size Groups)

          1.1. STRUCTURE and REGULATION OF THE VIRAL CYCLE

                    1.1.1. Structure and composition of viral particles: the capsid

                    1.1.2. Structure and composition of viral particles: the genome

                    1.1.3. Introduction to the viral cycle

                    1.1.4. Adsorption and penetration

                    1.1.5. Regulation of gene expression

                    1.1.6. Assembly, maturation and release

          1.2. EPIDEMIOLOGY and VIRAL PATHOGENESIS

                    1.2.1. Principles of viral ecology and epidemiology

                    1.2.2. Viral pathogens: Coronaviruses

                    1.2.3. Viral pathogens: the FLU

                    1.2.4. Viral pathogens: the HIV and the AIDS epidemics

2. LABORATORY EXERCISES (Small-size Groups)

          2.1. Quantification of viral particles

          2.2. One Step Growth cycle: kinetics of phage infection and host dynamics

Activitats

Tipus d’activitat Hores amb professor Hores sense professor Hores virtuals amb professor Total
Lectura / comentari de textos 1,00 10,00 0 11,00
Prova d'avaluació 1,00 25,00 0 26,00
Sessió expositiva 15,00 10,00 0 25,00
Sessió pràctica 6,00 15,00 0 21,00
Total 23,00 60,00 0 83

Bibliografia

  • Norkin, Leonard C (cop. 2010 ). Virology : molecular biology and pathogenesis . Washington, D.C.: ASM Press. Catàleg
  • Mahy, B. W. J. (Brian W. J.) (cop. 2010 ). Desk encyclopedia of human and medical virology . Oxford: Academic. Catàleg
  • Mahy, B. W. J.|q(Brian W. J.) (cop. 2009). The Dictionary of virology (4th ed.). Boston: Elsevier/Academic Press. Catàleg
  • Storch, Gregory A (2000 ). Essentials of diagnostic virology . New York [etc.]: Churchill Livingstone. Catàleg
  • Fields, Bernard N. (cop. 1996 ). Fields virology (3rd ed). Philadelphia [Pa.] [etc.]: Lippincott-Raven. Catàleg
  • Webster, Robert G. (1994 ). Encyclopedia of virology . London [etc.]: Academic Press. Catàleg
  • Levy, Jay A (1994 ). Virology (3rd ed.). Englewood Cliffs: Prentice Hall. Catàleg
  • Dimmock, N.J (1994 ). Introduction to modern virology (4th ed.). Oxford [etc.]: Blackwell Science. Catàleg
  • Harper, David R (1994 ). Molecular virology . Oxford: Bios. Catàleg
  • White, David O (cop. 1994 ). Medical virology (4th ed.). San Diego [etc.]: Academic Press. Catàleg
  • Cann, Alan J (1993 ). Principles of molecular virology . London [etc.]: Academic Press. Catàleg
  • Burleson, Florence G (cop.1992 ). Virology : a laboratory manual . San Diego [etc.]: Academic Press. Catàleg
  • Matthews, R.E.F (1992 ). Fundamentals of plant virology . San Diego [etc.]: Academic Press. Catàleg
  • Dulbecco, Renato (1988 ). Virology (2nd edition). Philadelphia: Lippincott. Catàleg
  • Rao, V.C (1986 ). Environmental virology . Washington: American Society for Microbiology. Catàleg
  • Gerba, Charles P. (cop. 1982 ). Methods in environmental virology . New York [etc]: Marcel Dekker. Catàleg
  • Madigan, Michael T. Guerrero, Ricardo (cop. 2009 ). Brock biología de los microorganismos (12ª ed.). Madrid [etc.]: Pearson Educación. Catàleg

Avaluació i qualificació

Activitats d'avaluació:

Descripció de l'activitat Avaluació de l'activitat % Recuperable
Laboratory Exercises (Small-size Groups)
Attendance to lab exercises is mandatory to pass the course.
This activity will be evaluated by answering several questions related to the results obtained during the lab exercises (Small-size Groups).
25 No
Analysis and discussion of scientific papers (Large-size Groups) This activity will be evaluated through a series of questions related to the discussed papers. This activity contributes to a 15% of the final mark. This activity can be retaken. 15
Exam of the theoretical content (Large-size group lectures) The exam includes questions about all theoretical content of the course (Large-size Groups).

This activity contributes 60% to the final mark but ONLY if the student gets a mark higher than (or equal to) 4.

This activity can be retaken.
60

Qualificació

Evaluation is done through two main activities: a lab report and a final exam.
Attendance to laboratory exercises is mandatory to pass the course.

The final mark results from:

LAB REPORT (LR): This activity consists of answering questions about experimental results obtained during the correspondent laboratory exercises (Small-size Groups). The mark obtained in this activity contributes 25% to the final mark. This activity cannot be retaken.

PAPER DISCUSSION (PD): This activity consists of an exam with several questions related to the papers discussed in class. This activity contributes to the final mark by 15%. Students that get marks below 5 must retake the PD activity.

EXAM (EX): This exam encompasses all the theoretical content of the subject (Large-size Groups). The mark of this exam must be higher than (or equal to) 4 to contribute 60% to the final mark. Students that get marks below 5 must retake the exam.

The final mark results from the sum of both activities weighted by their contribution as follows: 25% LR + 15% DP + 60% EX. To pass the course, students should get a mark higher than (or equal to) 5.

REMEDIAL ACTIVITIES: Students that get a final mark <4 in the exam or <4 in the PD will be able to retake these activities. The laboratory exercise report cannot be retaken. Both retaken activities will have the same evaluation criteria and conditions set for the previous ones.

Criteris específics de la nota «No Presentat»:
To pass the course, students have to:

a) attend practical sessions (Lab exercises).
b) submit the Lab Report in due time.
c) complete the paper discussion exam
c) complete the final exam.

Students not attending the practical sessions and not submitting any of the evaluation activities will be considered as NON-PRESENTED.

Avaluació única:
This evaluation will consist on a single exam including questions related to all contents of the subject, namely: theroretical content, scientific papers discussed in class, and lab exercises. The number of questions for each part will be proportional to the contribution of each part to the final mark (e.g. 6 theoretical questions, 2 questions related to papers, and 2 on lab exercises).

Requisits mínims per aprovar:
To pass the course students should get a final mark higher than (or equal to) 5.

Tutoria

1) Presential scenario:

– Personal tutorial meetings will be done at the Aulari Comú after setting a date with the student.

2) Semi-presential and distance class scenario:

– Personal tutorial meetings will be done on-line through specific applications (Microsoft TEAMS, Google Meet, others).
– Personal communications will be done using electronic mail as usual.

3) Vulnerable students or students under temporal confinement will be attended as in scenario 2

Comunicacio i interacció amb l'estudiantat

Communication with students will be done using two platforms: a) The Forum in the Moodle for general aspects and notifications; and b) electronic mail for personal communications.

Both systems will be used in all scenarios.

Assignatures recomanades

  • Ampliació de biologia cel·lular
  • Bioenergètica i metabolisme
  • Biologia
  • Biologia molecular
  • Bioquímica
  • Biotecnologia vegetal
  • Ecologia microbiana
  • Fisiologia bacteriana
  • Fonaments de bioinformàtica
  • Genètica
  • Genòmica
  • Microbiologia
  • Microbiologia clínica
  • Pràctiques de biologia molecular
  • Pràctiques de microbiologia
  • Regulació metabòlica

Modificació del disseny

Modificació de les activitats:
1) Semi-presential scenario:

– Theoretical classes will be done following the recommendations of the Faculty regarding the attendance of students. By today, this involves splitting students into two groups: Group A that will attend the classes at the Faculty (presential activity); and Group B, which will attend the classes on-line using specific telematic channels (TEAMS or Google Meets). Both groups will alternate on a daily basis.

– All communications with students will be done using the News Forum in the Moodle and by electronic mail.

– Lab exercises will be maintained as usual except in case of a lockdown. In the case of temporal confinement, the lab exercises will be substituted by online exercises.


2) Distance teaching (No presential scenario):

Since no attendance of students is expected under this scenario, all expositive classes will be done using online channels. Communication and lab-exercises will be done as in the semi-presential scenario (see above).

Modificació de l'avaluació:
Semi-presential and distance teaching scenarios

Since no presential attendance of students is expected under temporal confinement or a complete lockdown, evaluation activities will be modified as follows:

1) Lab exercises will be evaluated through the completion of a report that will consist of five questions regarding the datasets from One-Step Growth experiments. This activity accounts for 25% of the final mark and it can not be retaken.

2) Final exam: It will consist in a 10-question exam covering all aspects of the subject except the lab-exercises. The document will be distributed online through a specific activity in the moodle platform. Students will have four hours to complete and deliver the exam through moodle. Corrected exams will be sent to students using the same platform. This activity can be retaken if the mark is <4. The retaken exam will follow the same regulations as the normal exam.


In both cases, the contribution of each activity on the final mark will be the same as in the normal scenario, that is, final exam 75% and lab-exercises report 25%. Only the final exam can be retaken.

Tutoria i comunicació:
Communication with students will be done using two platforms:
a) The Forum in the Moodle for general aspects and notifications; and b) electronic mail for personal communications.

Both systems will be used in all scenarios.